Table 2. Regression analysis between various clinical factors and the soluble epidermal growth factor receptor in T2DM group.

Variable	Univariate regression				Multivariate regression
	R	R2	β±SE	P value	Partial R2	β±SE	P value
Male sex	0.159	0.025	−5.112±3.166	0.110
Age	0.276	0.076	−0.358±0.124	0.005	0.001	−0.053±0.161	0.744
Height	0.211	0.044	0.376±0.175	0.034	0.001	−0.081±0.226	0.723
Body weight	0.125	0.016	0.148±0.117	0.207
Waist circumference	0.242	0.059	−0.337±0.172	0.054
Body mass index	0.002	0.000	−0.007±0.394	0.986
Smoking status
Current smoker	0.163	0.026	6.153±3.712	0.101
Former smoker	0.125	0.016	1.895±1.491	0.207
Never	0.229	0.053	−3.716±1.570	0.020	0.060	−3.988±1.425	0.006
Hypertension	0.108	0.012	−3.633±3.339	0.279
Dyslipidemia	0.129	0.017	−5.199±3.988	0.195
Coronary artery disease	0.110	0.012	−7.532±6.749	0.267
Cerebrovascular disease	0.075	0.006	5.140±6.772	0.450
Systolic BP	0.062	0.004	−0.056±0.089	0.535
Diastolic BP	0.038	0.001	0.060±0.157	0.705
Hemoglobin	0.162	0.026	1.602±1.002	0.113
HbA1c	0.470	0.221	3.440±0.646	<0.001	0.166	3.143±0.675	<0.001
Fasting glucose	0.407	0.166	0.110±0.024	<0.001	0.016	0.074±0.052	0.155
PP2 glucose	0.469	0.220	0.075±0.015	<0.001	0.001	−0.002±0.029	0.951
Fasting C-peptide	0.160	0.026	−6.801±4.258	0.113
PP2 C-peptide	0.450	0.202	−4.770±1.034	<0.001	0.001	0.685±2.491	0.784
Fasting insulin	0.256	0.066	−0.620±0.238	0.011	0.037	−0.785±0.359	0.032
PP2 insulin	0.410	0.168	−0.142±0.034	<0.001	0.005	−0.080±0.092	0.388
HOMA-IR	0.056	0.003	−0.310±0.558	0.579
HOMA-β	0.296	0.087	−0.102±0.033	0.003	0.028	0.141±0.075	0.065
Apolipoprotein A	0.072	0.005	−0.044±0.084	0.603
Apolipoprotein B	0.226	0.051	0.131±0.077	0.094
Triglyceride	0.198	0.039	0.013±0.006	0.045	0.004	−0.007±0.010	0.497
Total cholesterol	0.366	0.134	0.113±0.029	<0.001	0.081	0.107±0.033	0.002
Serum creatinine	0.274	0.075	4.337±1.517	0.005	0.014	1.976±1.451	0.178
Estimated GFR	0.012	0.001	−0.003±0.027	0.907
HDL-C	0.064	0.004	−0.075±0.118	0.527
LDL-C	0.272	0.074	0.092±0.033	0.006	0.001	−0.011±0.106	0.921

T2DM, type 2 diabetes mellitus; SE, standard error; BP, blood pressure; HbA1c, glycosylated hemoglobin; PP2, 2-hour postprandial; HOMA-IR, homeostatic model assessment of insulin resistance; HOMA-β, homeostatic model assessment of β-cell function; GFR, glomerular filtration rate; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol.