Table 1.

Relevant imaging parameters for the dMRI protocols investigated in the current study

	TR (ms)	MB factor	b values (s/mm2)	# of diffusion directions/shell	# of b0 images	# of slices	Slice orient	inter-slice shift (FOV)	time shift (us)
Pilot study	7400	2	1500	65	8	144	Sagittal	1/2	1920
HCP 1Tx	7000	2	1000/2000	64	15	132	Oblique axial	1/2	1920
HCP pTx	7400	2	1000/2000	64	15	144	Sagittal	1/2	1920
pTx MB3	4934	3	1000/2000	95	22	144	Sagittal	1/4	960
pTx MB4	3701	4	1000/2000	129	29	144	Sagittal	1/4	640

Other relevant imaging parameters that were kept constant for all protocols listed include 1.05 mm isotropic resolution, 71 ms echo time, 3-fold in-plane acceleration (iPAT3), 6/8 partial Fourier, 210(RO)×210(PE) mm² field of view, 0.82 ms echo spacing, and 1388 Hz/pixel bandwidth. For all of the HCP and pTx related acquisitions, the listed diffusion weighted and b0 images were acquired twice with inverted phase encode directions (ie Anterior-Posterior (AP) and PA) and the total acquisition was divided into 4 segments of ~10 minutes each. For the pilot study, the listed diffusion weighted and b0 images were acquired once with the AP phase encode direction, and another set of six b0 images were acquired with matched imaging parameters but with the PA phase encode direction.