TABLE 4.
Predictors of BSI Anxiety at baseline and change over time among caregivers
| Baseline | Rate of Change | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Predictor | Subgroup | Estimate | SE | P1 | P2 | Estimate | SE | P1 | P2 |
|
| |||||||||
| Caregiver Gender | Male | 54.21 | 2.51 | 0.0974 | .5117 | −2.01 | 2.82 | .4790 | .8488 |
|
| |||||||||
| Female | 52.42 | 1.16 | 0.0414* | −2.61 | 1.26 | .4790 | |||
|
| |||||||||
| Caregiver Education | 44.07 | 7.06 | 0.4023 | 1.70 | 7.90 | .8308 | |||
|
| |||||||||
| Patient Age at Baseline | 51.89 | 2.61 | 0.4716 | −1.88 | 2.87 | .5135 | |||
|
| |||||||||
| Number of Surgeries | 51.08 | 1.74 | 0.5369 | −3.15 | 2.13 | .1437 | |||
|
| |||||||||
| GH Peak Value | 53.36 | 1.33 | 0.0138* | −3.43 | 1.36 | .0142 | |||
|
| |||||||||
| Surgery Group | Catheter | 55.48 | 2.61 | 0.0401* | .1705f | −3.67 | 2.65 | .1709 | .7596a |
|
| |||||||||
| Resection | 52.54 | 1.25 | 0.0465* | .4128g | −2.28 | 1.34 | .0943 | .9907b | |
|
| |||||||||
| No | 49.60 | 3.34 | 0.9050 | −2.23 | 3.84 | .5630 | |||
|
| |||||||||
| Surgery | |||||||||
|
| |||||||||
| CSF diversion | No | 52.97 | 1.32 | 0.0278* | .7570 | −2.47 | 1.40 | .0813 | .9878 |
|
| |||||||||
| Yes | 52.27 | 1.83 | 0.2204 | −2.51 | 1.96 | .2053 | |||
|
| |||||||||
| Diabetes Insipidus | No | 52.27 | 1.58 | 0.1558 | .7050 | −3.96 | 1.70 | .0233 | .2592 |
|
| |||||||||
| Yes | 53.08 | 1.44 | 0.0363* | −1.37 | 1.51 | .3674 | |||
|
| |||||||||
| HI | Grade 0 | 52.06 | 2.58 | 0.4283 | 2.25 | 2.73 | .4138 | ||
|
| |||||||||
| Grade 1 | 51.45 | 2.07 | 0.4871 | .8547h | −1.76 | 2.04 | .3919 | .2444c | |
|
| |||||||||
| Grade 2 | 53.63 | 1.44 | 0.0144* | .5972i | −4.19 | 1.48 | .0061 | .0422d | |
|
| |||||||||
| Wechslera | |||||||||
|
| |||||||||
| Verbal Comprehension | 43.45 | 7.17 | 0.3635 | −9.26 | 8.36 | .2885 | |||
|
| |||||||||
| Perceptual Reasoning | 45.08 | 6.70 | 0.4646 | −5.40 | 7.86 | .4949 | |||
|
| |||||||||
| Working Memory | 46.40 | 6.99 | 0.6082 | −5.62 | 7.67 | .4676 | |||
|
| |||||||||
| Processing Speed | 46.53 | 6.08 | 0.5699 | −.69 | 7.30 | .9246 | |||
|
| |||||||||
| CPT-IIb | |||||||||
|
| |||||||||
| Omissions | 51.52 | 4.52 | 0.7383 | .89 | 6.74 | .8952 | |||
|
| |||||||||
| Commissions | 54.17 | 5.53 | 0.4540 | −10.58 | 6.61 | .1174 | |||
|
| |||||||||
| Hit RT | 55.17 | 5.67 | 0.3646 | −1.97 | 7.86 | .8037 | |||
|
| |||||||||
| Overall Index | 53.10 | 1.40 | 0.0303* | −3.21 | 1.74 | .0722 | |||
|
| |||||||||
| Groovedc Pegboard | |||||||||
|
| |||||||||
| Dominant Hand | 51.88 | 1.23 | 0.1298 | −2.72 | 1.33 | .0469 | |||
|
| |||||||||
| Nondominant Hand | 52.08 | 1.26 | 0.1027 | −2.81 | 1.42 | .0541 | |||
|
| |||||||||
| D-KEFSd | |||||||||
|
| |||||||||
| Inhibition Completion Time | 50.66 | 4.53 | 0.8854 | −5.39 | 6.00 | .3765 | |||
|
| |||||||||
| Inhibition Switching Completion Time | 43.20 | 4.15 | 0.1074 | 1.91 | 5.44 | .7284 | |||
|
| |||||||||
| CVLT-Ce | |||||||||
|
| |||||||||
| Total | 47.83 | 3.68 | 0.5578 | ||||||
|
| |||||||||
| Short Delay-Free Recall z-score | 52.25 | 1.32 | 0.0928 | ||||||
|
| |||||||||
| Long Delay-Free Recall z-score | 52.36 | 1.34 | 0.0826 | ||||||
|
| |||||||||
| BRIEFj | |||||||||
|
| |||||||||
| Behavioral Regulation Index (BRI) | 40.28 | 4.86 | 0.0488* | −5.06 | 6.24 | .4211 | |||
|
| |||||||||
| Working Memory | 44.87 | 4.49 | 0.2556 | −6.22 | 5.94 | .2990 | |||
|
| |||||||||
| Metacognition Index (MI) | 43.44 | 4.93 | 0.1871 | −8.13 | 6.21 | .1961 | |||
|
| |||||||||
| Global Executive Composite (GEC) | 39.75 | 4.28 | 0.0186* | −6.56 | 5.50 | .2375 | |||
|
| |||||||||
| BASC-2k | |||||||||
|
| |||||||||
| Externalizing Problems | 34.72 | 4.79 | 0.0019* | −2.02 | 5.58 | .7191 | |||
|
| |||||||||
| Internalizing Problems | 38.63 | 4.06 | 0.0061* | −4.86 | 5.20 | .3538 | |||
|
| |||||||||
| Attention Problems | 46.22 | 4.41 | 0.3935 | −3.27 | 5.74 | .5712 | |||
|
| |||||||||
| ABAS-IIl | |||||||||
|
| |||||||||
| General Adaptive Composite (GAC) | 61.91 | 6.28 | 0.0608 | .70 | 7.42 | .9255 | |||
Univariate linear mixed effects modeling for predictors of change;
p< .05
- Baseline P1 is for the difference between the group or subgroup mean and the normative mean
- Baseline P2 is for the difference between subgroup means, when applicable
- Rate of Change P1 is for investigating whether the rate of change for the corresponding group or subgroup is 0
- Rate of Change P2 is for the difference of the rates of change between subgroups, when applicable
To assess intelligence, children were assessed with an age appropriate Wechsler scale (i.e., WPPSI-III for children 3 to 5, WISCIV for children 6–16, and WAIS IV for children >=17).
Children under 6 were not administered the CPT-II.
Children under 5 were not administered the Grooved Pegboard.
Children under 8 were not administered the DKEFS.
Children under 6 were not administered the CVLT-C.
Difference in Anxiety scores between patients who received catheters versus and no surgery
Difference in Anxiety scores between patients who received resection versus no surgery
Difference in Anxiety scores between HI grade 0 and HI grade 1
Difference in Anxiety scores between HI grade 0 and HI grade 2
Behavior Rating Inventory of Executive Function (BRIEF) Parent Form
Behavior Assessment System for Children, 2nd Edition (BASC-2)
Adaptive Behavior Assessment System, 2nd Edition (ABAS-II)