Table 3.
Pearson correlations, simple and multiple regression models for the total cohort and by group, early and later in gestation. Dependent variable for regression is NB%fat
| Entire Cohort | Normal-Weight | Obese | |||||
|---|---|---|---|---|---|---|---|
| Early (n=54) |
Later (n=51) |
Early (n=27) |
Later (n=27) |
Early (n=27) |
Later (n=24) |
||
| Pre-Pregnancy BMI (kg/m2) | 0.12 | ||||||
| Total GWG (kg) | 0.07 | ||||||
| Fasting TG (mg/dL) | 0.47* | 0.56* | 0.04 | 0.48# | 0.60# | 0.55# | |
| 1-hr PPTG (mg/dL) | 0.57* | 0.54* | 0.14 | 0.27 | 0.71* | 0.63# | |
| 2-hr PPTG (mg/dL) | 0.57* | 0.58* | 0.21 | 0.47† | 0.69# | 0.61# | |
| TG-AUC (mg*min/dL) | 0.53* | 0.57* | 0.12 | 0.44† | 0.66# | 0.60# | |
| Fasting Glucose (mg/dL) | 0.08 | 0.25 | −0.10 | 0.07 | 0.05 | 0.29 | |
| 1-hr PP Glucose (mg/dL) | 0.25 | 0.26 | 0.05 | 0.29 | 0.36 | 0.11 | |
| 2-hr PP Glucose (mg/dL) | 0.40# | 0.43# | 0.26 | 0.35 | 0.39 | 0.50† | |
| Glucose-AUC (mg*min/dL) | 0.43# | 0.42# | 0.10 | 0.26 | 0.54† | 0.47† | |
| Total Cohort Early | Obese Early | ||||||
|---|---|---|---|---|---|---|---|
| β | p | R2 | β | p | R2 | ||
| Simple Regression | 0.22 | Simple Regression | 0.36 | ||||
| Fasting TG | 0.07 | ≤ 0.001 | Fasting TG | 0.08 | ≤ 0.01 | ||
| Multiple Regression | 0.32 | Multiple Regression | 0.58 | ||||
| Fasting TG | 0.06 | ≤ 0.01 | Fasting TG | 0.07 | ≤ 0.01 | ||
| GLUC-AUC | 0.001 | 0.1 | GLUC-AUC | 0.001 | 0.1 | ||
| Simple Regression | 0.32 | Simple Regression | 0.50 | ||||
| 1-hr PPTG | 0.06 | ≤ 0.001 | 1-hr PPTG | 0.08 | ≤ 0.001 | ||
| Multiple Regression | 0.35 | Multiple Regression | 0.57 | ||||
| 1-hr PPTG | 0.05 | ≤ 0.01 | 1-hr PPTG | 0.06 | ≤ 0.01 | ||
| GLUC-AUC | 0.0005 | 0.2 | GLUC-AUC | 0.001 | 0.1 | ||
| Total Obese Later: | Cohort Later: | ||||||
| β | p | R2 | β | p | R2 | ||
| Simple Regression | 0.31 | Simple Regression | 0.30 | ||||
| Fasting TG | 0.05 | ≤ 0.001 | Fasting TG | 0.05 | ≤ 0.01 | ||
| Multiple Regression | 0.33 | Multiple Regression | 0.36 | ||||
| Fasting TG | 0.04 | ≤ 0.01 | Fasting TG | 0.04 | 0.1 | ||
| GLUC-AUC | 0.0004 | 0.3 | GLUC-AUC | 0.001 | 0.3 | ||
| Simple Regression | 0.29 | Simple Regression | 0.40 | ||||
| 1-hr PPTG | 0.05 | ≤ 0.001 | 1-hr PPTG | 0.05 | ≤ 0.01 | ||
| Multiple Regression | 0.32 | Multiple Regression | 0.44 | ||||
| 1-hr PPTG | 0.04 | ≤ 0.01 | 1-hr PPTG | 0.05 | < 0.05 | ||
| GLUC-AUC | 0.0004 | 0.2 | GLUC-AUC | 0.001 | 0.3 | ||
Data are Pearson correlation (r-values) with NB%Fat;
*
indicates p≤0.001,
#
indicates p≤0.01,
†
indicates p<0.05; GWG= Gestational Weight Gain; PP = postprandial; AUC = area-under-the-curve; IR = insulin resistance; OGTT = oral glucose tolerance test. Fasting FFA (r=0.22); Fasting Insulin (r=0.07); HOMA-IR (r=0.11) for total cohort (all p>0.05) so not added to table.