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The presence of the genes IL-1B and IL-1RN combined with Helicobacter pylori infection is associated with hypochlorydria and thus reducing the risk for gastroesophageal reflux disease. GERD: Gastroesophageal reflux disease; H. pylori: Helicobacter pylori; IL-1B-511*T: Interleukin-1 beta T allele; IL-1RN: Gene encoding for a non-signaling molecule IL-1 receptor antagonist (IL-1Ra).
