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. 2018 Aug 23;8:12706. doi: 10.1038/s41598-018-29711-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Physical characterization of MIONs. (a) Dynamic light scattering (DLS) of (1) JHU MIONs – 55 nm, (2) Si-MIONs – 81 nm and (3) AuSi-MIONs – 145 nm. (b) SQUID magnetometry measurements of magnetization of MIONs as a function of external field strength. Data are normalized by total solid content, without removal of the silica and gold contributions. (c) Transmission electron microscopy (TEM) of (1) JHU MION cores, (2) silica-coated MIONs and (3) gold and silica-coated MIONs.