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. 2018 Aug 17;12:70. doi: 10.3389/fnana.2018.00070

FIGURE 4.

FIGURE 4

Differences in the laminar distribution of large pyramids across areas in the human cerebral cortex. (A–D) The largest pyramidal neurons in limbic area 24 in the subgenual cingulate cortex are in layer V (arrows); pyramids in layer III are comparatively smaller (arrowhead). (E–H) The largest pyramidal neurons in eulaminate area 46 in the dorsolateral prefrontal cortex are in layer III (arrows), while pyramids in layers V area smaller (arrowhead). Pyramids in layer V of limbic area 24 (C,D) are overall smaller than pyramids in layer III of eulaminate area 46 (F,G). WM, white matter. Roman numerals indicate cortical layers. Calibration bar in (E) applies to (A,E). Calibration bar in (H) applies to (B–D,F–H). (This figure is a reexamination of material from an earlier paper; Zikopoulos et al., 2018).