Differences in the distribution of large pyramids in the rhesus macaque and rat cerebral cortex. (A–C) The largest pyramidal neurons in limbic area 24 in the subgenual cingulate cortex of the rhesus macaque are in layer V (long arrow), while pyramids in layer III are comparatively smaller (short arrow). (D–F) Pyramidal neurons in eulaminate area 46 in the dorsolateral prefrontal cortex of the rhesus macaque are slightly larger in layer III (long arrow) than in layer V (short arrow). (G–I) The largest pyramidal neurons in agranular area Cg3 of the rat cortex are in layer V (long arrow), while pyramids in layer III are smaller (short arrow). (J–L) The largest pyramidal neurons in granular area HL of the rat cortex are also found in layer V (long arrow) and pyramids in layer III are smaller (short arrow). Cg3, cingulate area 3; HL, hind limb area; WM, white matter. Roman numerals indicate cortical layers. Calibration bar in (J) applies to (A,D,G,J). Calibration bar in (L) applies to (B,C,E,F,H,I,K,L). (A–F) of this figure are a reexamination of material from an earlier paper (Zikopoulos et al., 2018); (G–L) are a reexamination of material form a gift of Dr. Alan Peters.