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. 2018 Aug 17;12:573. doi: 10.3389/fnins.2018.00573

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Copyright © 2018 At least a portion of this work is authored by EH, SS, KR, NS, MK, MI, SJ, and CP on behalf of the U.S. Government and, as regards EH, SS, KR, NS, MK, MI, SJ, CP, and the U.S. Government, is not subject to copyright protection in the United States.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volume, spatial extent and heterogeneity of focal DTI abnormalities at different times after mCCI. Volume values are plotted (A) for ROI masks generated based on Trace (triangles) and FA (circles) grouped according to time after injury. For values from brains with cavitation, points have been shaded in blue instead of black. Groupwise ROI overlay maps (B) combining all ROI masks within a group in a common space are shown to provide a visualization of the extent and heterogeneity of focal lesions at different times after mCCI. The sample size is given for each group and the color scale indicates the number of brains with a detectable abnormality at each voxel.