Skip to main content
. 2018 May 24;72(4):897–904. doi: 10.1007/s11418-018-1222-x

Table 2.

The P-gp inhibition rate of seven crude drugs constituting YKS

Crude drug Composition ratio of crude drug in YKS (%) Concentration of crude drug in YKS (μg/ml)a Contribution rate (%)b
Uncariae uncis cum ramulus 14.6 284 53.1
Glycyrrhizae radix 7.4 143 1.7
Atractylodis lanceae rhizoma 19.5 378 15.3
Poria 19.5 378 14.7
Angelicae acutilobae radix 14.6 284 3.0
Cnidii rhizoma 14.6 284 7.4
Bupleuri radix 9.8 189 4.8
Total 100.0 1,940 100.0

aConcentration of each crude drug in the IC50 concentration (1.94 mg/ml) of YKS extract was calculated from the composition ratio of seven crude drugs constituting YKS

bThe contribution rate of each crude drug was calculated as a percentage of the total inhibition at each concentration included in the YKS (IC50 concentration) by using the correlative formulas described in result section and Fig. 2