Table 2.
Differentially regulated proteins at CB129ΔslpB in relation to CB 129 wild-type.
| Accession | Score | Description | LOG(2) ratio fold-change | Anova (p) | COG biological process |
|---|---|---|---|---|---|
| UP-REGULATED PROTEINS | |||||
| PFCIRM129_09610 | 41.9018 | Protein of unknown function | 6.16 | 0.006 | Coenzyme transport and metabolism and Signal transduction mechanisms |
| PFCIRM129_09540 | 37.0751 | Protein of unknown function | 5.43 | 0.003 | Transcription |
| PFCIRM129_09590 | 102.7882 | Protein of unknown function | 4.53 | 0.002 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_09465 | 51.2086 | Protein of unknown function | 4.33 | 0.005 | – |
| PFCIRM129_09585 | 90.2656 | Protein of unknown function | 4.10 | 0.006 | General function prediction only |
| PFCIRM129_04060 | 38.8837 | Guanylate kinase, Guanosine monophosphate kinase (GMP kinase) | 3.83 | 0.033 | Nucleotide transport and metabolism |
| PFCIRM129_09570 | 44.4682 | Protein of unknown function | 3.69 | 0.003 | Cell motility |
| PFCIRM129_07005 | 243.5985 | DNA ligase (NAD+) | 3.32 | 0.009 | Replication, recombination and repair |
| PFCIRM129_01620 | 59.7705 | Stomatin/prohibitin | 2.96 | 0.036 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_10485 | 35.443 | Spermidine synthase | 2.76 | 0.011 | Amino acid transport and metabolism |
| PFCIRM129_10870 | 30.3436 | Protein of unknown function | 2.09 | 0.033 | General function prediction only |
| PFCIRM129_09930 | 56.3355 | Hypothetical protein | 2.06 | 0.004 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_09935 | 87.1427 | Aldo/keto reductase | 2.02 | 0.001 | Secondary metabolites biosynthesis, transport and catabolism |
| PFCIRM129_08225 | 203.0233 | 50S ribosomal protein L2 | 1.84 | 0.018 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_05110 | 60.8023 | Nuclease of the RecB family | 1.80 | 0.039 | Replication, recombination and repair |
| PFCIRM129_02560 | 52.268 | Transcriptional regulator | 1.61 | 0.041 | Coenzyme transport and metabolism |
| PFCIRM129_08430 | 75.8136 | Pyruvate flavodoxin/ferredoxin oxidoreductase | 1.55 | 0.040 | Energy production and conversion |
| PFCIRM129_09920 | 380.2718 | Hypothetical secreted protein | 1.37 | 0.008 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_04715 | 57.0906 | Hypothetical protein | 1.36 | 0.008 | Signal transduction mechanisms |
| PFCIRM129_09175 | 100.5874 | NAD-dependent epimerase/dehydratase | 1.33 | 0.038 | General function prediction only |
| PFCIRM129_12405 | 136.3375 | UDP-glucose 4-epimerase | 1.29 | 0.041 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_01790 | 34.8378 | 3-dehydroquinate dehydratase | 1.27 | 0.010 | Amino acid transport and metabolism |
| PFCIRM129_07890 | 128.6333 | Putative O-sialoglycoprotein endopeptidase | 1.26 | 0.048 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_00585 | 212.5378 | Polyphosphate glucokinase | 1.24 | 0.048 | Transcription and Carbohydrate transport and metabolism |
| PFCIRM129_07790 | 140.7785 | Cysteine synthase 1 | 1.23 | 0.020 | Amino acid transport and metabolism |
| PFCIRM129_09600 | 51.9916 | Protein of unknown function | 1.21 | 0.034 | Replication, recombination and repair |
| PFCIRM129_11300 | 522.5826 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose 4 phosphate dehydrogenase | 1.21 | 0.030 | Carbohydrate transport and metabolism |
| PFCIRM129_00690 | 23.8969 | Protein of unknown function | 1.14 | 0.049 | Function unknown |
| PFCIRM129_01510 | 22.4775 | Carbohydrate or pyrimidine kinases PfkB family | 1.14 | 0.040 | Carbohydrate transport and metabolism |
| PFCIRM129_03870 | 27.4108 | Glutamine-dependent NAD(+) synthetase | 1.08 | 0.036 | General function prediction only |
| PFCIRM129_00225 | 85.9906 | 16S rRNA processing protein | 1.06 | 0.028 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_11255 | 221.963 | Pyridoxal biosynthesis lyase pdxS | 1.06 | 0.047 | Coenzyme transport and metabolism |
| PFCIRM129_03920 | 293.1815 | Pyridine nucleotide-disulphide oxidoreductase | 1.05 | 0.013 | Energy production and conversion |
| PFCIRM129_07930 | 409.5736 | Glucosamine–fructose-6-phosphate aminotransferase (Hexosephosphate aminotransferase, D-fructose-6-phosphate amidotransferase) | 1.04 | 0.031 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_11805 | 158.7382 | Magnesium (Mg2+) transporter | 1.03 | 0.013 | Inorganic ion transport and metabolism |
| PFCIRM129_08045 | 417.9752 | DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase subunit alpha) | 1.01 | 0.004 | Transcription |
| DOWN-REGULATED PROTEINS | |||||
| PFCIRM129_06035 | 66.5616 | Enolase 2 | −1.09 | 0.010 | Carbohydrate transport and metabolism |
| PFCIRM129_06325 | 41.3227 | Trypsin-like serine protease | −1.13 | 0.015 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_00315 | 221.1159 | Beta-lactamase-like:RNA-metabolizing metallo-beta-lactamase | −1.21 | 0.031 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_04530 | 19.2011 | Hypothetical protein | −1.23 | 0.045 | Function unknown |
| PFCIRM129_06605 | 17.9867 | Metal-dependent hydrolase | −1.29 | 0.032 | General function prediction only |
| PFCIRM129_10030 | 162.9893 | DNA repair protein | −1.32 | 0.042 | Replication, recombination and repair |
| PFCIRM129_06500 | 87.9342 | Hypothetical protein | −1.33 | 0.048 | Nucleotide transport and metabolism |
| PFCIRM129_10650 | 33.3856 | Hypothetical protein | −1.33 | 0.045 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_03835 | 79.2532 | Pyrazinamidase/nicotinamidase | −1.37 | 0.019 | Coenzyme transport and metabolism and Signal transduction mechanisms |
| PFCIRM129_10070 | 83.9023 | Hypothetical protein | −1.39 | 0.024 | General function prediction only |
| PFCIRM129_00245 | 381.851 | GTP binding signal recognition particle protein | −1.45 | 0.031 | Intracellular trafficking, secretion, and vesicular transport |
| PFCIRM129_05955 | 85.1759 | Peptide-methionine (S)-S-oxide reductase | −1.46 | 0.009 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_09830 | 327.7897 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) | −1.49 | 0.042 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_09395 | 77.9918 | Protein of unknown function | −1.50 | 0.035 | Replication, recombination and repair |
| PFCIRM129_07355 | 38.1315 | Hypothetical protein | −1.59 | 0.036 | Amino acid transport and metabolism |
| PFCIRM129_02750 | 19.5802 | Anti-sigma factor | −1.61 | 0.010 | Transcription |
| PFCIRM129_09840 | 37.8042 | Glutamyl-tRNA(Gln) amidotransferase subunit C (Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C) | −1.71 | 0.045 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_12290 | 113.782 | Hypothetical protein | −1.73 | 0.023 | Translation, ribosomal structure and biogenesis |
| PFCIRM129_02880 | 157.3643 | Zn dependant peptidase | −1.82 | 0.002 | General function prediction only |
| PFCIRM129_01675 | 171.214 | Flavin-containing amine oxidase | −1.82 | 0.013 | Amino acid transport and metabolism |
| PFCIRM129_00465 | 78.5201 | Thiamine biosynthesis protein | −1.90 | 0.047 | Coenzyme transport and metabolism |
| PFCIRM129_09980 | 56.8929 | Peptidyl-prolyl cis-trans isomerase | −1.91 | 0.019 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_02370 | 174.428 | L-aspartate oxidase (LASPO) (Quinolinate synthetase B) | −1.94 | 0.010 | Coenzyme transport and metabolism |
| PFCIRM129_05120 | 33.1399 | Putative carboxylic ester hydrolase | −1.99 | 0.020 | Lipid transport and metabolism |
| PFCIRM129_04475 | 54.968 | Transporter | −2.01 | 0.026 | Function unknown |
| PFCIRM129_12425 | 80.5954 | Protein of unknown function FUZZYLOCATION = TRUE | −2.02 | 0.025 | Transcription |
| PFCIRM129_04980 | 227.0852 | D-alanine–D-alanine ligase (D-alanylalanine synthetase) | −2.05 | 0.005 | Cell wall/membrane/envelope biogenesis and General function prediction only |
| PFCIRM129_11215 | 88.6965 | Dioxygenase | −2.12 | 0.047 | Inorganic ion transport and metabolism and Secondary metabolites biosynthesis, transport and catabolism |
| PFCIRM129_10195 | 96.8755 | Transcriptional regulator | −2.12 | 0.036 | Transcription |
| PFCIRM129_08985 | 30.4822 | Hypothetical protein | −2.13 | 0.042 | General function prediction only |
| PFCIRM129_04260 | 287.3443 | DNA polymerase III alpha subunit | −2.15 | 0.038 | Replication, recombination and repair |
| PFCIRM129_02065 | 15.789 | Ferrous iron uptake protein A 9.a.8.1.x | −2.25 | 0.022 | Inorganic ion transport and metabolism |
| PFCIRM129_04725 | 106.5589 | Hypothetical protein | −2.27 | 0.032 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_05460 | 489.2107 | Surface protein with SLH domain | −2.29 | 0.039 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_04925 | 12.884 | Hypothetical protein | −2.29 | 0.028 | Carbohydrate transport and metabolism |
| PFCIRM129_10690 | 9.166 | Protein of unknown function | −2.37 | 0.049 | Function unknown |
| PFCIRM129_05620 | 65.4691 | MscS transporter, small conductance mechanosensitive ion channel | −2.43 | 0.044 | Cell wall/membrane/envelope biogenesis |
| PFCIRM129_06895 | 73.9719 | Thiredoxine like membrane protein | −2.49 | 0.024 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_10610 | 181.5134 | Phosphocarrier, HPr family | −2.54 | 0.021 | Signal transduction mechanisms and Carbohydrate transport and metabolism |
| PFCIRM129_02565 | 36.2455 | Hypothetical protein | −2.57 | 0.039 | Defense mechanisms |
| PFCIRM129_00850 | 58.5524 | Cation-transporting ATPase | −2.59 | 0.005 | Inorganic ion transport and metabolism |
| PFCIRM129_02970 | 142.4983 | Hypothetical protein | −2.60 | 0.016 | Energy production and conversion |
| PFCIRM129_00010 | 145.5914 | Argininosuccinate lyase (Arginosuccinase) | −2.65 | 0.004 | Amino acid transport and metabolism |
| PFCIRM129_02590 | 36.8971 | Hypothetical transmembrane protein | −2.71 | 0.013 | Inorganic ion transport and metabolism |
| PFCIRM129_02910 | 44.2268 | Hypothetical protein | −2.74 | 0.039 | Replication, recombination and repair |
| PFCIRM129_10040 | 39.9232 | Hypothetical protein | −2.78 | 0.048 | Carbohydrate transport and metabolism |
| PFCIRM129_12235 | 1098.1026 | Internaline A | −2.80 | 0.041 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_00040 | 20.5108 | N-acetyl-gamma-glutamyl-phosphate reductase (AGPR) (N- acetyl-glutamate semialdehyde dehydrogenase) (NAGSA dehydrogenase) | −2.99 | 0.002 | Amino acid transport and metabolism |
| PFCIRM129_03005 | 41.8204 | Hypothetical protein | −3.01 | 0.035 | Secondary metabolites biosynthesis, transport and catabolism |
| PFCIRM129_05445 | 69.2875 | Transcriptional Regulator, TetR family | −3.09 | 0.036 | Transcription |
| PFCIRM129_02960 | 83.486 | Cold shock-like protein CspA | −3.36 | 0.031 | Transcription |
| PFCIRM129_00705 | 46.3689 | Surface protein of unknown function | −3.42 | 0.016 | – |
| PFCIRM129_08670 | 192.0452 | Cell-wall peptidases, NlpC/P60 family secreted protein | −3.80 | 0.000 | General function prediction only |
| PFCIRM129_03390 | 45.4963 | Superfamily II RNA helicase | −4.01 | 0.019 | Replication, recombination and repair |
| PFCIRM129_06155 | 35.4 | Hypothetical protein | −4.03 | 0.004 | Carbohydrate transport and metabolism |
| PFCIRM129_06085 | 371.7356 | Transcription-repair coupling factor | −4.07 | 0.004 | Replication, recombination and repair and Transcription |
| PFCIRM129_01360 | 47.9803 | NUDIX hydrolase | −4.17 | 0.012 | Nucleotide transport and metabolism |
| PFCIRM129_11775 | 48.0011 | Surface protein D with SLH domain | −4.70 | 0.020 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_00700 | 461.2371 | Surface layer protein B (S-layer protein B) | −5.10 | 0.009 | Posttranslational modification, protein turnover, chaperones |
| PFCIRM129_11140 | 154.2908 | Type I restriction-modification system DNA methylase | −5.58 | 0.005 | Defense mechanisms |
| PFCIRM129_04135 | 15.2209 | Uncharacterized ATPase related to the helicase subunit of the holliday junction resolvase | −5.82 | 0.006 | Replication, recombination and repair |