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. 2018 Aug 14;9:890. doi: 10.3389/fphar.2018.00890

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Copyright © 2018 Huang, Huang, Luo, Zhou, Tao, Chen, Song, Chen and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plot of 2-3 NRTI plus LPV /r in virologic suppression. Each risk ratio represents the effect of the second-line treatment in people with HIV with previous ART failure. (A) Intention-to-treat analysis of HIV RNA <400 copies/mL. (B) Pre-protocal analysis of HIV RNA <400 copies/mL. NRTI, nucleoside/nucleotide reverse transcriptase inhibitor; LPV /r, Ritonavir-boosted lopinavir.