Table 1.

Frequency of kinase alterations in SR ALL

Subgroup	NCI SR, n (%) (n = 1023)
Ph-like ALL	139 (13.6)
CRLF2-R	41 (4)
IGH-CRLF2	5 (0.5)
P2RY8-CRLF2	36 (3.5)
CRLF2-R with JAK-STAT mutation	14 (1.7)
CRLF2-R without JAK-STAT mutation	27 (2.6)
Non-CRLF2	98 (9.6)
ABL1-class fusions	2 (0.2)
JAK2-R	2 (0.2)
EPOR-R	0
NTRK3-R	1 (0.1)
Other JAK-STAT	2 (0.2)
Ras	6 (0.6)
No kinase identified	56 (5.5)
Not tested	29 (2.8)

ABL1-class: ZMIZ1-ABL1, EBF1-PDGFRB. JAK2-R: ETV6-JAK2, PAX5-JAK2. NTRK3: ETV6-NTRK3. Other JAK-STAT: IL7R. Ras: KRAS, NRAS.