Table 1.
Demographic characteristics of the hemodialysis group (pre HD) and the control group: comparison of basic situation and baseline data (Mean ± SD)
| Pre HD | HD Group | Control Group | P value |
|---|---|---|---|
| Male [eyes (percentage)] | 54 (60.00%) | 60 (63.83%) | 0.593 |
| Female [eyes (percentage)] | 36 (40.00%) | 34 (36.17%) | |
| Age (year) | 57.78 ± 13.57 | 54.90 ± 17.60 | 0.239 |
| Systolic pressure (mmHg) | 147.14 ± 22.43 | 133.65 ± 18.64 | 0.016* |
| Diastolic pressure (mmHg) | 83.75 ± 16.03 | 75.28 ± 11.79 | 0.022* |
| Urea (mmol/L) | 24.330 ± 7.853 | 5.275 ± 0.936 | < 0.001** |
| Creatinine (umol/L) | 891.10 ± 70.78 | 77.00 ± 20.38 | < 0.001** |
| Uric acid (umol/L) | 427.50 ± 79.78 | 367.88 ± 85.441 | 0.012* |
| Na (mmol/L) | 138.20 ± 2.64 | 142.00 ± 2.45 | < 0.001** |
| K (mmol/L) | 4.860 ± 0.920 | 4.191 ± 0.217 | < 0.001** |
| Ca (mmol/L) | 2.279 ± 0.206 | 2.283 ± 0.070 | 0.908 |
| P (mmol/L) | 1.849 ± 0.542 | 1.160 ± 0.180 | < 0.001** |
| Mg (mmol/L) | 1.050 ± 0.129 | 0.873 ± 0.035 | < 0.001** |
| PTH (ng/L) | 479.70 ± 419.20 | 40.30 ± 12.45 | < 0.001** |
| Fasting plasma glucose (mmol/L) | 7.725 ± 3.356 | 5.433 ± 0.695 | < 0.001** |
| Spherical power (D) | 0.088 ± 0.508 | −2.4011 ± 3.7786 | 0.012* |
| Cylinder power (D) | −0.857 ± 0.138 | −0.6711 ± 0.6071 | 0.070 |
| logMAR of BCVA | 0.100 ± 0.0282 | − 0.0205 ± 0.2344 | 0.345 |
| TBUT(s) | 6.957 ± 0.861 | 9.171 ± 5.801 | 0.949 |
| Schirmer’s I test (mm) | 12.014 ± 2.020 | 16.934 ± 9.617 | 0.309 |
| IOP (mmHg) | 12.855 ± 0.420 | 15.01 ± 3.69 | 0.073 |
| ACD (mm) | 2.642 ± 0.073 | 2.783 ± 0.481 | 0.082 |
| CT (μm) | 575.18 ± 5.859 | 549.11 ± 38.67 | 0.650 |
| ECD (cell/mm2) | 2758.47 ± 35.494 | 2707.46 ± 194.91 | 0.055 |
| ECS (μm2) | 363.16 ± 6.577 | 371.34 ± 29.27 | 0.132 |
| ECSCV | 40.717 ± 1.573 | 40.88 ± 7.35 | 0.381 |
| LT (mm) | 4.146 ± 0.064 | 3.979 ± 0.460 | 0.120 |
| CSF (μm) | 244.36 ± 4.464 | 249.68 ± 32.75 | 0.080 |
| SIM (μm) | 312.22 ± 2.912 | 323.45 ± 22.49 | 0.350 |
| NIM (μm) | 310.28 ± 2.904 | 322.13 ± 21.33 | 0.220 |
| IIM (μm) | 311.14 ± 3.990 | 316.29 ± 17.85 | 0.022* |
| TIM (μm) | 302.88 ± 4.233 | 310.79 ± 19.39 | 0.030* |
| SOM (μm) | 276.82 ± 3.915 | 280.42 ± 16.98 | 0.475 |
| NOM (μm) | 289.25 ± 2.368 | 294.61 ± 19.35 | 0.428 |
| IOM (μm) | 267.27 ± 5.037 | 266.45 ± 19.31 | 0.204 |
| TOM (μm) | 259.62 ± 5.432 | 262.37 ± 20.73 | 0.290 |
| Average RT (μm) | 273.40 ± 3.302 | 276.39 ± 17.37 | 0.164 |
| RNFL thickness (μm) | 90.65 ± 1.829 | 96.24 ± 23.06 | 0.669 |
| CHT (μm) | 289.55 ± 11.385 | 232.87 ± 65.23 | 0.302 |
PTH Parathyroid hormone, TBUT Tear break-up time, logMAR Logarithmic minimum angle of resolution, BCVA Best corrected visual acuity, IOP Intraocular pressure, ACD Anterior chamber depth, LT Lens thickness, CT Corneal thickness, ECD Endothelial cell density, ECS Endothelial cell size, ECSCV Endothelial cell size variation coefficient, CSF Central subfield, SIM Superior inner macula, NIM Nasal inner macula, IIM Inferior inner macula, TIM Temporal inner macula, SOM Superior outer macula, NOM Nasal outer macula, IOM Inferior outer macula, TOM Temporal outer macula, MV Macular volume, RNFL Retinal nerve fiber layer, CHT Choroidal thickness, *: P < 0.05; **: P<0.01