Table 1.

Baseline characteristics and scores

Characteristic	All Patients	Good sleepers (PSQI< 5)	Poor sleepers (PSQI≥5)
Age, years	N = 128	N = 35	N = 71
Mean (SD)	41.5 (11.3)	40.4 (11.8)	41.3 (10.7)
Median (range)	41.0 (19–70)	41.0 (19–61)	41.0 (19–65)
Gender, n (%)	N = 128	N = 35	N = 71
Women	91 (71.1)	21 (60.0)	53 (74.7)
Men	37 (28.9)	14 (40.0)	18 (25.4)
Diagnosis, n (%)	N = 128	N = 35	N = 71
RRMS	114 (89.1)	31 (88.6)	62 (87.3)
CIS	14 (10.9)	4 (11.4)	9 (12.7)
Duration of disease, months	N = 113	N = 32	N = 61
Mean (SD)	43.0 (71.6)	30.9 (63.8)	45.6 (74.3)
Median (range)	6.9 (0.1–315.1)	6.9 (0.3–262.3)	6.3 (0.1–315.1)
EDSS, median (range)	N = 128	N = 35	N = 71
	2.0 (0–5)	2.0 (0–5)	2.0 (0–5)
MFIS	N = 122	N = 35	N = 71
Mean (SD)	32.38 (20.33)	20.20 (15.24)	39.38 (18.78)
Median (range)	34.0 (0.0–76.0)	18.0 (0.0–51.0)	43.0 (2.0–76.0)
SF-36 physical component score	N = 113	N = 33	N = 67
Mean (SD)	44.56 (11.35)	50.86 (8.37)	41.80 (11.41)
Median (range)	46.53 (16.50–64.06)	53.00 (22.67–64.06)	41.21 (16.50–60.67)
SF-36 mental component score	N = 113	N = 33	N = 67
Mean (SD)	41.74 (13.28)	47.84 (9.98)	38.27 (13.31)
Median (range)	44.39 (12.44–63.82)	50.96 (22.76–63.82)	39.54 (12.44–59.53)
HADS-D	N = 128	N = 35	N = 71
HADS-D ≥ 8, n (%)	29 (22.66)	2 (5.71)	25 (35.21)
HADS-A	N = 128	N = 35	N = 71
HADS-A ≥ 8, n (%)	41 (32.03)	4 (11.43)	32 (45.07)
ESS	N = 118	N = 35	N = 68
Mean (SD)	8.03 (4.54)	6.69 (4.26)	8.88 (4.71)
Median (range)	8.0 (0.0–16.0)	6.0 (0.0–14.0)	9.0 (1.0–16.0)

Subgroups of good sleepers (PSQI< 5) and poor sleepers (PSQI≥5) do not add up to N = 128 (100%) due to missing PSQI baseline values

PSQI Pittsburgh Sleep Quality Index, SD standard deviation, RRMS relapsing-remitting multiple sclerosis, CIS clinically isolated syndrome, EDSS Expanded Disability Status Scale, MFIS Modified Fatigue Impact Scale, SF-36 Short Form 36, HADS Hospital Anxiety and Depression Scale, ESS Epworth Sleepiness Scale