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. 2018 Nov 22;7:1042. Originally published 2018 Jul 10. [Version 2] doi: 10.12688/f1000research.15486.2

Figure 4. Number of significant disease modules identified with FDR thresholds 0.05 and 0.1,

Figure 4.

and from three different inter-layer weightings: No Weights, i.e., equal weights for all layers (585 modules in total), Confidence Weights, i.e., weights proportional to the expected biological relevance: 1-ppi=1, 2-ppi=1, 3-path=1, 4-coexpr=0.5, 5-cancer=0.1, 6-homology=0.1 (555 modules in total), and Inverse Confidence Weights, i.e., weights inversely proportional to the expected biological relevance: 1-ppi=0.1, 2-ppi=0.1, 3-path=0.1, 4-coexpr=0.5, 5-cancer=1, 6-homology=1 (648 modules in total).