Table 2.
Logistic regression analysis of associations between AURKA rs2273535 polymorphism and risk of gastric cancer.
| Genotype | Cases∗(n = 385) |
Controls∗(n = 470) |
OR (95% CI) | P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| AT vs. AA | 163/182 | 42.3/47.3 | 177/261 | 37.7/55.5 | 1.32 (0.99,1.76) | 0.056 |
| TT vs. AA | 36/182 | 9.3/47.3 | 30/261 | 6.4/55.5 | 1.72 (1.02,2.90) | 0.041 |
| TT vs. AT+AA | 36/345 | 9.3/89.6 | 30/438 | 6.4/93.2 | 1.30 (0.77,2.21) | 0.327 |
| TT+AT vs. AA | 199/182 | 51.6/47.3 | 207/261 | 44.1/55.5 | 1.38 (1.05,1.81) | 0.020 |
| T vs. A | 235/527 | 30.5/68.4 | 237/699 | 25.2/74.4 | 1.32 (1.06,1.63) | 0.012 |
∗The genotyping was successful in 381 cases and 468 controls. Bold values are statistically significant (P < 0.05).