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. 2018 Jul 28;31(3 Suppl):97S–214S. doi: 10.1293/tox.31.97S

Figure 47.

Figure 47.

Atrophy, optic nerve; mouse. Loss of axons associated with glial cell proliferation (“gliosis”) and posterior bowing of the optic nerve head and lamina cribosa (cupping of the optic nerve).