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Necrosis, tympanic membrane; middle ear; guinea pig. Coagulative necrosis of the tympanic membrane in a guinea pig. The tympanic membrane (arrows) is homogeneously eosinophilic and surrounded by intense inflammatory infiltrates on both the external and internal sides. TB = Tympanic bulla lumen; EEC = External ear canal; C = Cochlea. Wrinkles in section are artifact of the GMA sectioning and placement on water bath.
