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. 2018 Aug;13(8):1396–1407. doi: 10.4103/1673-5374.235293

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Copyright: © Neural Regeneration Research

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Apocynin markedly increased Cx43 protein expression in OGD-exposed astrocytes and in rats with cerebral ischemia/reperfusion injury (western blot assay).

Representative immunoblots and semi-quantitative analysis of Cx43 protein levels (A, B). Data are expressed as the mean ± SD (n = 3 per group; one-way analysis of variance followed by the Tukey-Kramer multiple comparison test). **P < 0.01, ***P < 0.001, vs. OGD/R + vehicle/MCAO + vehicle group; ###P < 0.001, vs. control/sham group. Cx43: Connexin 43; OGD: oxygen/glucose deprivation; OGD/R: oxygen/glucose deprivation/reoxygenation; MCAO: middle cerebral artery occlusion; GAPDH: glyceraldehyde-3-phosphate dehydrogenase.