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. 2018 Aug;13(8):1477–1485. doi: 10.4103/1673-5374.235306

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Copyright: © Neural Regeneration Research

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Electron microscopy analysis of sciatic nerves in the novel CNC model.

Electron micrographs of sciatic nerves at the compression site at 8, 12 and 20 weeks post-operation. (A–C) Sham-operated nerves, and (D–F) compressed nerves at 8, 12, and 20 weeks post-operation in the NBCA-treated pup group (n = 15). (G–I) Sham-operated nerves, and (J–L) compressed nerves at 8, 12, and 20 weeks post-operation in the NBCA-treated adult group (n = 15). Scale bars: 1 μm. (M, N) Quantification of the thickness of myelin sheaths in the NBCA-treated pup (M) and adult (N) groups. All data are represented as the mean ± SD (repeated measures one-way analysis of variance followed by Dunnett's post hoc test). ***P < 0.001. NBCA: N-butyl-cyanoacrylate; CNC: chronic nerve compression.