Figure 1.

Acupuncture improved spatial learning and memory ability of SAMP8 mice in the Morris water maze.

(A) Escape latency of mice in each group in the hidden platform trial. (B) Retention time of mice in each group in the probe trial. (C) Escape latency of mice in each group in the reversal trial. Data are expressed as the mean ± SD (n = 10). Escape latency in the Morris water maze was analyzed by repeated measures two-way analysis of variance. Comparison between groups was performed using one-way analysis of variance followed by post hoc Bonferroni testing (multiple comparisons). *P < 0.05, **P < 0.001, vs. SAMR1 group; #P < 0.05, ##P < 0.001, vs. SAMP8 group. SAMP8: Senescence-accelerated mouse prone 8; SAMR1: senescence-accelerated mouse resistant 1.