Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of Daily Exposure of f-ara-a (AUC0-24) in the Observed Data Presented by Fludarabine Daily Regimen
| Fludarabine Regimen | n | AUC0-24, median (range), mg*hour/L |
|---|---|---|
| All dose regimens | 133 | 3.7 (3.3-4.5) |
| 40 mg/m2/dose | 55 | 4.5 (3.7-4.8) |
| mg/kg/dose* | 38 | 3.4 (3.1-3.9) |
Patients assigned to a regimen of 40 mg/m2/day but had empiric dose reductions and dosing based on a mg/kg basis. Daily doses range from .9-1.33 mg/kg/dose.
