Table 5.
Mammalian cell cytotoxicity of selected compounds
Analogues | % Cell viability found on incubation with HEK 293 cell line |
||
---|---|---|---|
1 μg/ml | 10 μg/ml | 100 μg/ml | |
10b | 103 | 106 | 118 |
10f | 107 | 88 | 72 |
10k | 102 | 71 | 63 |
12c | 123 | 102 | 73 |
27a | 107 | 114 | 115 |
28a | 104 (2) | 92 (2) | 85 (2) |