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. 2018 Aug 20;14:1445–1451. doi: 10.2147/TCRM.S172071

Table 3.

Clinical factors associated with inhospital mortality of CMV colitis patients without IBD (31 patients with full-length colonoscopy)

Characteristics Odd ratio 95% confidence interval p-value
Age 1.036 0.993–1.081 0.104
Gender (male/female) 0.188 0.035–1.000 0.050
Immunological status 0.286 0.056–1.466 0.133
Underlying diseases
 Liver cirrhosis 0.000 0.000 1.000
 End-stage renal disease 5.923×109 0–>1012 0.999
 Diabetes mellitus 3.600 0.655–19.78 0.141
 HIV infection 0.000 0.000 0.999
Immunosuppressive medication
 Immunosuppressant 2.625 0.146–47.183 0.513
 Chemotherapy 4.443 0–>1012 1.000
 Steroid 0.500 0.083–3.011 0.449
Laboratory data
 Total white blood cell count,/µL 1.000 1.000 0.934
 Hemoglobin level, g/dL 0.690 0.436–1.091 0.112
 Platelet count, ×1,000/mm3 0.993 0.984–1.003 0.164
 ALT, IU/L 0.957 0.886–1.034 0.267
 Bilirubin, mg/dL 1.508 0.827–2.750 0.180
 Albumin, g/dL 0.308 0.055–1.736 0.182
 C-reactive protein, mg/dL 1.009 0.997–1.022 0.146
Involved area
 Right-sided colitis (n=12, 35.3%) 0.343 0.058–2.036 0.239
 Left-sided colitis (n=8, 23.5%) 0.268 0.028–2.578 0.254
 Pancolitis (n=11, 32.4%) 6.800 1.233–37.497 0.028*
Endoscopic finding
 Colitis with/without erosion, only
 Ulcer 2.353 0.235–23.601 0.467
  Well-demarcated small ulcer 0.863 0.254–2.932 0.813
  Longitudinal ulcer 1.667 0.254–10.931 0.594
  Semi-lunate ulcer 2.051 0.647–6.501 0.222
  Irregular ulcer 1.978 0.533–7.340 0.308
  Deep ulcer (including punch-out ulcer) 1.469 0.372–5.811 0.583
  Ulcer coating with white membrane 3.810 0.757–19.172 0.105
  Segmental mucosal defect 0.943 0.253–3.520 0.930
 Pseudomembrane 4.443×109 0–>1012 1.000
 Tumor/polyp-like 1.250 0.099–15.796 0.863
 Cobblestone appearance 0.563 0.054–5.864 0.630
 Skip lesions 1.071 0.206–5.584 0.935
Ganciclovir or valganciclovir treatment 9.693×108 0–.1012 0.999
 Treatment duration 0.937 0.830–1.057 0.287

Note:

*

p<0.05.

Abbreviations: ALT, alanine transaminase; CMV, cytomegalovirus; HIV, human immunodeficiency virus; IBD, inflammatory bowel disease.