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. 2018 Aug 20;10:2799–2807. doi: 10.2147/CMAR.S170526

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© 2018 Dong et al. This work is published and licensed by Dove Medical Press Limited

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The relationship between TINCR and TRIP13 in prostate cancer.

Notes: (A) TINCR expression is markedly negatively correlated with TRIP13 mRNA expression in prostate cancer tissue samples from TCGA database. (B) Levels of TINCR expression are negatively associated with TRIP13 mRNA expression in prostate cancer tissue samples from our study. (C) Immunohistochemical staining of TRIP13 in prostate cancer tissues: a, low-expression of TRIP13; b, high-expression of TRIP13. (D) The efficiency of pcDNA-TINCR is confirmed by qRT-PCR in LNCaP. (E) The efficiency of pSilencer-TINCR is confirmed by qRT-PCR in DU145. (F) Upregulation of TINCR expression reduces TRIP13 mRNA expression in LNCaP cell, and downregulation of TINCR expression increases TRIP13 mRNA expression in DU145 cell. (G) Upregulation of TINCR expression decreases TRIP13 mRNA expression in LNCaP cell, and downregulation of TINCR expression elevates TRIP13 mRNA expression in DU145 cell.

Abbreviations: qRT-PCR, quantitative RT-PCR; TINCR, terminal differentiation-induced non-coding RNA; TCGA, The Cancer Genome Atlas.