Table S1.
Comparisons of demographic and clinical characteristics between participants with and without LOY in the schizophrenia group
| SCZ with LOY (n=13) |
SCZ without LOY (n=80) |
P-value | |
|---|---|---|---|
| Age (years) (median [IQR]) | 68.0 [66.0–76.0] | 65.0 [60.0–72.0] | 0.077a |
| Duration of illness (years) (median [IQR]) | 49.0 [43.0–53.0] | 38.0 [27.0–44.3] | 0.0016a |
| Smoking (never/former/current) | 4/4/5 | 18/28/34 | 0.602b |
| Antipsychotic dose (mg/day) (median [IQR])c | 600.0 [325.0–976.0] | 610.0 [368.8–1,265.6] | 0.561a |
Notes:
a
P-value calculated using the Mann–Whitney U-test.
b
P-value calculated using the Cochran–Armitage trend test.
c
Antipsychotic dose was calculated based on chlorpromazine equivalents.
Abbreviations: LOY, loss of chromosome Y; SCZ, schizophrenia; IQR, interquartile range.