Table 3.
Incidence of all-cause, cardiovascular-, cancer- and diabetes-related mortality, and CVD events, in individuals with diabetes, by screening group (2001 to 2012)
| Variable | Screening group (n = 13,992) | No-screening group (n = 125,083) | Crude HR (95% CI) | Adjusted HRa (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
| Number of events | Person-years follow-up | Rate per 1000 person-years (95% CI) | Number of events | Person-years follow-up | Rate per 1000 person-years (95% CI) | |||
| All-cause mortality | 1775 | 97,265 | 18.2 (17.4, 19.1) | 19,739 | 801,019 | 24.6 (24.3, 25.0) | 0.71 (0.68, 0.75) | 0.79 (0.74, 0.84) |
| Cardiovascular mortality | 509 | 97,265 | 5.2 (4.8, 5.7) | 5835 | 801,019 | 7.3 (7.1, 7.5) | 0.70 (0.64, 0.77) | 0.80 (0.72, 0.88) |
| Cancer mortality | 954 | 97,265 | 9.8 (9.2, 10.5) | 9546 | 801,019 | 11.9 (11.7, 12.2) | 0.79 (0.74, 0.84) | 0.83 (0.77, 0.89) |
| Diabetes-related mortality | 121 | 97,265 | 1.2 (1.0, 1.5) | 1701 | 801,019 | 2.1 (2.0, 2.2) | 0.57 (0.48, 0.69) | 0.66 (0.54, 0.81) |
| Composite cardiovascular event (first of CVD death, non-fatal IHD or non-fatal stroke) | 2854 | 86,317 | 33.1 (31.9, 34.3) | 28,487 | 698,893 | 40.8 (40.3, 41.2) | 0.78 (0.75, 0.81) | 0.84 (0.80, 0.89) |
aHRs were estimated with a Cox proportional hazards regression model. Robust standard errors were calculated that take into account the two-level structure of the data and any potential correlation between individuals within practices
Models were adjusted for age, sex, education and prevalent chronic disease (IHD, stroke, cancer); baseline hazards were stratified by county