Table 2. Longitudinal association between hypertension and psoriasis incidence.

	Univariate Cox			Multivariate Coxa
	HR	95% Cl	P	HR	95% Cl	P
Hypertension	1.54	1.47–1.61	< 0.001	1.18	1.08–1.28	< 0.001
Age (year)
20–39	1			1
40–64	1.35	1.24–1.45	< 0.001	1.32	1.22–1.43	< 0.001
≥ 65	1.26	1.16–1.38	< 0.001	1.27	1.16–1.39	< 0.001
Male	1.10	1.05–1.14	< 0.001	1.17	1.12–1.22	< 0.001
Antihypertensive medication
ACEi	1.46	1.34–1.59	< 0.001	1.07	0.99–1.16	0.102
ARB	1.55	1.43–1.69	< 0.001	1.00	0.91–1.10	0.979
ß-blocker	1.45	1.36–1.55	< 0.001	1.08	0.98–1.20	0.115
CCB	1.55	1.46–1.64	< 0.001	1.14	1.05–1.23	0.002
Thiazide	1.48	1.40–1.57	< 0.001	1.10	1.02–1.18	0.010
Diabetes	1.34	1.24–1.46	< 0.001	1.08	0.99–1.17	0.095
Dyslipidemia	1.64	1.51–1.78	< 0.001	1.28	1.17–1.40	< 0.001

^aMultivariate Cox regression analyses are adjusted for age, sex, household income, residential area, comorbidities of diabetes and dyslipidemia, current nonsteroidal anti-inflammatory drug use, and antihypertensive medication.

Abbreviations: ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; CI, confidence interval; HR, hazard ratio.