Table 3. Longitudinal association between hypertension and psoriasis incidence according to age and sex.

	Sex		Age		Age < 65 years		Age ≥ 65 years
	Male	Female	< 65 years	≥ 65 years	Male	Female	Male	Female
Hypertension	1.14(1.01–1.29)	1.19(1.05–1.35)	1.20(1.09–1.32)	1.06(0.89–1.27)	1.16(1.01–1.33)	1.23(1.07–1.42)	1.06(0.82–1.37)	1.07(0.83–1.36)
Antihypertensive medication
ACEi	1.09(0.98–1.25)	0.92(0.79–1.06)	0.99(0.89–1.11)	1.04(0.85–1.27)	1.09(0f.93-1.26)	0.90(0.76–1.07)	1.12(0.84–1.50)	0.98(0.74–1.30)
ARB	1.19(1.04–1.36)	0.99(0.85–1.14)	1.05(0.94–1.18)	1.14(0.90–1.43)	1.17(1.01–1.37)	0.95(0.81–1.12)	1.22(0.87–1.70)	1.07(0.78–1.48)
ß-blocker	1.09(0.97–1.22)	1.05(0.94–1.18)	1.03(0.94–1.13)	1.21(1.02–1.42)	1.06(0.93–1.20)	1.01(0.89–1.14)	1.22(0.96–1.56)	1.20(0.96–1.51)
CCB	1.11(0.99–1.24)	1.19(1.07–1.33)	1.20(1.09–1.31)	0.98(0.83–1.15)	1.18(1.01–1.30)	1.27(1.11–1.45)	0.98(0.77–1.23)	0.98(0.79–1.23)
Thiazide	0.98(0.87–1.09)	1.22(1.11–1.34)	1.14(1.05–1.24)	1.00(0.87–1.15)	0.99(0.88–1.13)	1.28(1.14–1.43)	0.92(0.74–1.14)	1.07(0.88–1.28)
Diabetes	1.07(0.95–1.19)	1.13(0.99–1.29)	1.07(0.96–1.18)	1.15(0.98–1.35)	1.03(0.90–1.18)	1.12(0.96–1.31)	1.16(0.93–1.45)	1.14(0.98–1.43)
Dyslipidemia	1.26(1.11–1.43)	1.31(1.16–1.49)	1.28(1.16–1.41)	1.34(1.09–1.64)	1.33(1.16–1.52)	1.21(1.05–1.40)	0.91(0.64–1.31)	1.68(1.31–2.15)

Values are expressed as hazard ratios (95% confidence interval). Cox regression analyses are adjusted for age, sex, household income, residential area, comorbidities of diabetes and dyslipidemia, nonsteroidal anti-inflammatory drug use, and antihypertensive medication.

Abbreviations: ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker.