Figure 4.

A Patterned Progression in Immune Cell Composition

(A) The coefficient of variance (CV) for 21 gated cell populations in healthy adults (n = 3), preterm (n = 29), and term (n = 15) children.

(B) The relative proportions of 10 cell populations in 183 postnatal blood samples from 57 children ordered by sampling day of life.

(C) Composition of immune cell clusters analyzed using self-organizing map clustering of the B cell population.

(D) The B cell cluster #6 on a bhSNE analysis of total B cells and relative CD38, CD9, and CD24 expression.

(E) The relative frequency of cluster B #6 over time in children. Shaded area represents the confidence interval around the mean.

(F) Frequency of cluster B #6 in parents.

See also Figure S4.