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. 2018 Jul 23;126(7):077006. doi: 10.1289/EHP3441

Figure 2.

Figures 2A, 2B, 2C, 2D, 2E, and 2F are graphical representations of differential imprinted gene 5-hmC peaks by BPA exposure for Gnas, Grb10, Plagl1, Klf14, Pde10a, and Snrpn, respectively.

Differential imprinted gene 5-hmC peaks by BPA exposure. 5-hmC coverage was visualized at six imprinted loci with significant BPA-related DHMRs: (A) Gnas; (B) Grb10; (C) Plagl1; (D) Klf14; (E) Pde10a; and (F) Snrpn. 5-hmC levels are shown for matched 2-, 4-, and 10-month blood samples, as indicated by y-axis labels. Blue and red peaks represent forward and reverse strand 5-hmC enrichment, respectively. The Gnas, Plagl1, and Pde10a DHMRs occurred on the forward strand, whereas the Grb10, Klf14, and Snrpn DHMRs occurred on the reverse strand.