Table 2.
Chr | Start | End | Gene ID | Gene Name | Location | Direction with BPA exposure | csaw score | FDR |
---|---|---|---|---|---|---|---|---|
chr2 | 174315451 | 174315750 | 14683 | Gnas | Intronic | 113.4 | ||
chr11 | 12004801 | 12005100 | 14783 | Grb10 | Intronic | 70.5 | ||
chr10 | 13130651 | 13131050 | 22634 | Plagl1 | Exonic | 60.7 | ||
chr6 | 30957751 | 30958050 | 619665 | Klf14 | Exonic | 55.9 | ||
chr17 | 8746901 | 8747050 | 23984 | Pde10a | intronic | 50.1 | ||
chr17 | 12828001 | 12828550 | 104103 | Airn | Intronic | 16.2 | 0.02 | |
chr13 | 24335001 | 24335150 | 12763 | Cmah | Intronic | 13.1 | 0.05 | |
chr7 | 60207401 | 60207600 | 20646 | Snrpn | Intronic | 13.0 | 0.05 | |
chr6 | 5079501 | 5079850 | 243725 | Ppp1r9a | Intronic | 12.8 | 0.05 | |
chr7 | 143348051 | 143348350 | 16535 | Kcnq1 | Intronic | 11.5 | 0.07 | |
chr10 | 13402051 | 13402250 | 215789 | Phactr2 | Intronic | 11.3 | 0.07 | |
chr13 | 108963951 | 108964200 | 238871 | Pde4d | Intronic | 10.1 | 0.10 |
Note: List of imprinted loci with annotated, significant () DHMRs generated from csaw modeling results. For csaw results, a transformed FDR is used for the score, such that ; higher score indicates a larger degree of significance (lower FDR value). Additionally, direction of effect by BPA exposure is shown, with a () indicating increased 5-hmC with BPA exposure and a () indicating decreased 5-hmC with BPA exposure. BPA, bisphenol-A; Chr, chromosome; DHMR, differentially hydroxymethylated region; FDR, false discovery rate; ID, identification.