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. 2018 Jul 19;42(4):2020–2030. doi: 10.3892/ijmm.2018.3787

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Copyright: © Zou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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MgiG regulates the expression of genes in the oxidative stress pathway. (A) mRNA expression levels of Mt1, PRDX1 and SOD2. (B) Protein expression levels of Mt1, PRDX1 and SOD2, measured by western blotting. Representative blots and quantification is shown. Results were normalized to GAPDH. Data are presented as mean ± standard deviation (n=10 mice per group; n=3 for in vitro results). ^##P<0.01 and ^###P<0.001 compared with control; ^*P<0.05, ^**P<0.01 and ^***P<0.001 compared with oxaliplatin alone. MgiG, magnesium isoglycyrrhizinate; Mt1, metallothionein 1; PRDX1, peroxiredoxin 1; SOD2, superoxide dismutase 2; Oxa, oxaliplatin.