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. 2018 Jul 20;42(4):2062–2070. doi: 10.3892/ijmm.2018.3790

Figure 2.

Figure 2

Identified dysregulated miR-FFL motifs in the sub-network. (A) Different colors correspond to the different type of nodes in each dysregulated sub-network, including miRNAs (yellow), genes (blue) and TFs (red). (B) The number of miR-FFLs, TFs, genes and miRNAs among the cardiac hypertrophy-associated miR-FFLs are illustrated in the bar graph. (C) Pie chart showing the proportion of cardiac hypertrophy-associated miR-FFLs among all the background miR-FFLs. (D) Significantly dysregulated sub-networks associated with AMI. (E) Bar graph showing the number of miR-FFLs, TFs, genes and miRNAs among the AMI-associated miR-FFLs. (F) Pie chart showing the proportion of AMI-associated miR-FFLs among all the background miR-FFLs. miR-FFL, microRNA-associated feed-forward loops; TFs, transcription factors; AMI, acute myocardial infarction.