Table III.
Thirteen prognostic pathways identified by LASSO estimation-based univariate Cox-proportional hazards model.
| Pathways | Coefficient | HR | P-value |
|---|---|---|---|
| BIOCARTA_HIVNEF_PATHWAY | 0.113 | 1.002 | <0.001 |
| KEGG_ARACHIDONIC_ACID_METABOLISM | 3.310 | 3.168 | <0.001 |
| KEGG_AXON_GUIDANCE | 2.784 | 2.124 | 0.001 |
| KEGG_CYTOKINE-CYTOKINE_RECEPTOR_INTERACTION | 0.609 | 1.021 | 0.002 |
| KEGG_ENDOCYTOSIS | 0.647 | 1.118 | 0.003 |
| KEGG_FOCAL_ADHESION | 1.666 | 1.460 | 0.001 |
| KEGG_INSULIN_SIGNALING_PATHWAY | −1.653 | 0.322 | 0.001 |
| KEGG_NITROGEN_METABOLISM | 2.046 | 1.769 | 0.001 |
| KEGG_O-GLYCAN_BIOSYNTHESIS | 1.133 | 1.391 | 0.001 |
| KEGG_PATHWAYS_IN_CANCER | 2.272 | 1.889 | 0.001 |
| KEGG_TYPE_II_DIABETES_MELLITUS | 2.394 | 2.081 | 0.001 |
| KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 1.875 | 1.682 | 0.002 |
| KEGG_CELL_ADHESION_MOLECULES | 3.288 | 2.963 | 0.002 |
LASSO, least absolute shrinkage and selection operator; HR, hazard ratio.