Figure 6.
Comparison of platelet aggregation induced by ristocetin and collagen in the baseline sample and sheared samples. In this aggregation test, 300 μlof whole blood was mixed with 300 μl of saline solution with or without 3mM CaCl2intest cells and 50 μl of ristocetin (final concentration of 0.77mg/ml) or 25 μl of collagen (final concentration of 3.2ug/ml) was used to induce platelet aggregation. (A) The impedance curves of ristocetin-induced platelet aggregation of the baseline and four sheared samples; (B) The quantitative comparison of ristocetin-induced platelet aggregation of the baseline and sheared blood samples (n=6, *P<0.05); (C) The impedance curves of collagen-induced platelet aggregation of the baseline and four sheared blood samples; (D) The quantitative comparison of collagen-induced platelet aggregation of the baseline and sheared samples (n=6, *P<0.05).