Table 3.
Participants (N = 17,966) | Non-participants (N = 50,544) | Participants vs. non- participants | ||||
---|---|---|---|---|---|---|
No. of cases | Rate per 100,000 person-years† (95% CI) | No. of cases | Rate per 100,000 person-years† (95% CI) | Adjusted relative risk (95% CI)†† | P value | |
Liver cancer incidence | 57 | 79.4 | 104 | 54.6 | 1.21 (0.88, 1.68) | 0.244 |
Sex | ||||||
Male | 52 | 134.2 | 91 | 109.5 | 1.21 (0.86, 1.70) | 0.275 |
Female | 5 | 13.1 | 13 | 12.3 | 1.13 (0.40, 3.20) | 0.813 |
Age in 2012 (years) | ||||||
35–49 | 17 | 57.2 | 30 | 25.0 | 1.46 (0.80, 2.66) | 0.215 |
50–64 | 30 | 86.5 | 74 | 92.0 | 1.13 (0.77, 1.66) | 0.530 |
Calendar year | ||||||
2012 | 15 | 115.0 | 25 | 55.2 | 1.95 (1.02, 3.71) | 0.042 |
2013 | 11 | 55.6 | 22 | 45.1 | 1.03 (0.50, 2.14) | 0.931 |
2014 | 16 | 73.1 | 24 | 49.8 | 1.36 (0.72, 2.57) | 0.346 |
2015 | 15 | 80.9 | 33 | 61.6 | 0.89 (0.48, 1.65) | 0.721 |
All-cause mortality | 274 | 376.2 | 699 | 369.7 | 0.91 (0.79, 1.04) | 0.167 |
Liver cancer mortality | 33 | 44.9 | 69 | 36.2 | 1.04 (0.68, 1.58) | 0.856 |
Sex | ||||||
Male | 33 | 84.7 | 59 | 70.9 | 1.18 (0.77, 1.80) | 0.456 |
Female | 0 | 0.0 | 10 | 9.4 | 0 | N/A |
Age in 2012 (years) | ||||||
35–49 | 11 | 37.0 | 17 | 14.1 | 1.66 (0.77, 3.56) | 0.193 |
50–64 | 22 | 63.3 | 52 | 64.6 | 0.88 (0.53, 1.45) | 0.611 |
*The median follow-up time for incidence was 4.0 years (interquartile range, 3.8 to 4.0), and for mortality was 4.0 years (interquartile range, 3.8 to 4.0).
†Incidence rate per 100 000 person-years, standardized to age distribution of person-years experienced by all residents using 5-year age categories.
††Adjusted for sex and age. For analyses stratified by sex, models were only adjusted for age. For analyses stratified by age, models were only adjusted for sex.