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. 2018 Aug 24;8:12787. doi: 10.1038/s41598-018-31119-9

Table 5.

Liver cancer stage according to serological results and liver ultrasonography, 2012–2015.

Cancer stage (BCLC) Total
0 or A B C D missing
HBsAg status at baseline
 Negative
  Cases of liver cancer (no.) 3 2 5 3 1 14
  Deaths from liver cancer (no. %) 1 (33.3) 2 (100.0) 5 (100.0) 3 (100.0) 0 (0.0) 11 (84.6)
 Positive
  Cases of liver cancer (no.) 10 13 14 4 2 43
  Deaths from liver cancer (no. %) 2 (20.0) 7 (53.8) 11 (78.6) 2 (50.0) 0 (0.0) 22 (51.2)
Among HBsAg-positive group only
AFP (baseline)
 Negative
  Cases of liver cancer (no.) 7 11 11 4 2 35
  Deaths from liver cancer (no. %) 1 (14.3) 6 (54.5) 8 (72.7) 2 (50.0) 0 (0.0) 17 (48.6)
 Positive
  Cases of liver cancer (no.) 3 2 3 0 0 8
  Deaths from liver cancer (no. %) 1 (33.3) 1 (50.0) 3 (100.0) 0 (0.0) 0 (0.0) 5 (62.5)
AFP (baseline + follow-up)
 Negative
  Cases of liver cancer (no.) 6 8 8 2 2 26
  Deaths from liver cancer (no. %) 1 (16.7) 3 (37.5) 6 (75.0) 1 (50.0) 0 (0.0) 11 (42.3)
 Positive
  Cases of liver cancer (no.) 4 5 6 2 0 17
  Deaths from liver cancer (no. %) 1 (25.0) 4 (80.0) 5 (83.3) 1 (50.0) 0 (0.0) 11 (64.7)
Ultrasonography (baseline)
 Normal
  Cases of liver cancer (no.) 1 0 4 0 1 6
  Deaths from liver cancer (no. %) 0 (0.0) 0 (0.0) 3 (75.0) 0 (0.0) 0 (0.0) 3 (50.0)
 Abnormal
  Cases of liver cancer (no.) 3 6 8 2 0 19
  Deaths from liver cancer (no. %) 0 (0.0) 3 (50.0) 7 (87.5) 1 (50.0) 0 (0.0) 11 (57.9)
 Missing
  Cases of liver cancer (no.) 6 7 2 2 1 18
  Deaths from liver cancer (no. %) 2 (33.3) 4 (57.1) 1 (50.0) 1 (50.0) 0 (0.0) 8 (44.4)
Ultrasonography (baseline + follow-up)
 Normal
  Cases of liver cancer (no.) 0 0 0 0 0 0
  Deaths from liver cancer (no. %) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Abnormal (any)
  Cases of liver cancer (no.) 6 9 12 3 1 31
  Deaths from liver cancer (no. %) 0 (0.0) 4 (44.4) 9 (75.0) 1 (33.3) 0 (0.0) 14 (45.2)
 Missing (all)
  Cases of liver cancer (no.) 4 4 2 1 1 12
  Deaths from liver cancer (no. %) 2 (50.0) 3 (75.0) 2 (100.0) 1 (100.0) 0 (0.0) 8 (66.7)

Abbreviations: AFP, alpha-fetoprotein; BCLC, Barcelona Clinic Liver Cancer; HBsAg, Hepatitis B virus surface antigen.