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. 2018 Aug 24;8:12715. doi: 10.1038/s41598-018-30579-3

Figure 1.

Figure 1

Schema for annotation of different types of molecular alterations in esophageal squamous cell carcinoma. The research articles published on esophageal squamous cell carcinoma (ESCC) are screened to filter the differentially expressed molecules at DNA, mRNA, miRNA and protein levels in ESCC tissues/cell lines as compared with their normal cell line or adjacent normal epithelia. The screened articles fulfilling the criteria described in the schema are manually curated to catalog the molecular alternations at DNA, mRNA, miRNA, and protein level. The information pertaining to ESCC and gene regulation status, the experimental approach used, analysis design, region of sample collection and along with the PubMed citation is provided for each molecule. The molecules are provided with external link to other database like OMIM, HPRD, HGNC and Ensembl to additional information about the molecule.