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. 2018 Aug 24;8:12738. doi: 10.1038/s41598-018-31121-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Glomerular endothelial cells in vitro and wound healing analysis. (A) Immunofluorescence for DAPI (blue), cMet (green), and CD31 (red) was observed in healthy human glomeruli. Original magnification: X400. (B) The levels of phosphorylated cMet were increased in the glomeruli from patients with diabetic nephropathy compared with those from normal control subjects; DAPI (blue), phospho-cMet (red). Original magnification: X400. (C) Assessment of the endothelial cell migratory capacity was assessed using a scratch wound healing assay between 0 and 30 hours. There was a significant difference in the migratory potential of the cMet group compared to the control and HGF groups.