Table 1.
Demographic and clinical characteristics of the patients with successful genotyping (n = 594).
| Patient characteristics | Median (IQR) | Range |
|---|---|---|
| Age [years] | 44.1 (36.7, 51.2) | 18.5–59.3 |
| Body Mass Index (BMI) [kg/m2] | 27.9 (24.5, 31.8) | 11.2–51.32 |
| Length of hospital stay [months] | 4 (3, 4) | 1–7 |
| Alcohol consumption [g/week] | 16 (0, 89) | 0.0–216 |
| Age at onset [year] | 26 (21, 32) | 9.0–56.0 |
| Clinicians Global Impression (CGI)- Severity | 4 (3, 4) | 1–7 |
| Duration of antipsychotic treatment [years] | 13.0 (6.0, 22.0) | 0.0–43.0 |
| Duration of illness [years] | 14.8 (8.0, 23.3) | 0.2–43.6 |
| n | % | |
| Gender | ||
| Male | 336 | 56.7 |
| Female | 258 | 43.4 |
| Psychosis onset | ||
| Early psychosis onset (≤18 yr old) | 62 | 10.4 |
| Late onset (>18 yr old) | 452 | 76.9 |
| Unknown | 75 | 12.6 |
| Smoking | ||
| Yes (every day or sometimes) | 239 | 40.2 |
| No (never or quit)* | 298 | 50.1 |
| Unknown | 57 | 9.6 |
| Presence of psychiatric disease in first-degree relative | ||
| Yes | 201 | 33.8 |
| No | 318 | 53.5 |
| Unknown | 75 | 12.6 |
| Main psychiatric diagnoses | ||
| Schizophrenia | 306 | 51.5 |
| Schizoaffective disorder | 49 | 8.2 |
| Delusion | 26 | 4.4 |
| Psychosis unspecified | 84 | 14.1 |
| Bipolar disorder | 26 | 4.4 |
| Other | 49 | 8.2 |
| Undiagnosed psychosis | 54 | 17.8 |
| Antipsychotic medication | ||
| None | 60 | 10.1 |
| Multitherapy | 42 | 7.1 |
| Risperidone | 91 | 15.3 |
| Olanzapine | 108 | 18.2 |
| Zuclopenthixol | 48 | 8.1 |
| Perphenazine | 56 | 9.4 |
| Haloperidol | 49 | 8.2 |
| Clozapine | 57 | 9.6 |
| Aripiprazole | 73 | 12.3 |
| Quetiapine | 33 | 5.6 |
| Ziprasidone | 17 | 2.9 |
| Flupentixol | 16 | 2.7 |
| Unknown | 83 | 14.0 |
| Mood stabilizers | 65 | 10.9 |
Clinical Global Impression–Severity (CGI-S) was available from 513 of the patients. *Of this group, ~45% had quit smoking.