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. 2018 Mar 16;89(9):983–988. doi: 10.1136/jnnp-2017-317833

Table 5.

Types of MBDs in children from AED-exposed mothers

Type of MBD Affected babies (n) AEDs Supposed diagnosis
Ventricular septal defect 3 GBP; GBP; PGB Epi; Epi; Psy
Atrial septal defect, tricuspid insufficiency 1 LTG Epi
Bilateral postaxial polydactyly 1 CBZ Epi
Ectopic kidney 1 CNZ Psy
Congenital diaphragmatic hernia 1 CBZ Epi
Multiple congenital anomalies+hypospadias 1 PB+ETS Epi

AED, antiepileptic drug; CBZ, carbamazepine; CNZ, clonazepam; Epi, epilepsy; ETS, ethosuximide; GBP, gabapentin; LTG, lamotrigine; MBD, major birth defects; PB, phenobarbital; PGB, pregabalin; Psy, psychiatric disorder.