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. 2018 Aug 25;18:7. doi: 10.1186/s12907-018-0074-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Crystal Deposits. a Calcium pyrophosphate (CPP). Synovial sclerosis with large amount of CPP (× 100), CPP positive birefringent crystals with rhomboid shape under polarized light, inset (× 200). b Monosodium urate. Macrophage and giant cell reaction to fascicles of dissolved urate crystals (black arrow) (H&E × 200), residual negative birefringent crystals under polarized light in inset (× 400). c Oxalate. Deposition of oxalate crystals in bone marrow in a case of primary oxaluria (H&E × 200). Positive birefringent crystals under polarized light in inset (× 400). d Cholesterol. Clefts of cholesterol crystals in long-standing chronic bursitis with macrophage reaction with numerous foamy forms to particulate wear debris of MoM THA implant (H&E × 200). e Hydroxyapatite (calcinosis). Spherical and targetoid deposits of calcium hydroxyapatite in calcific bursitis of shoulder joint (H&E × 200). f Hydroxyapatite (calcinosis). Bone marrow stromal reaction to deposits of calcium hydroxyapatite (black arrow) with brisk osteoblatic activity and thick osteoid seam (white arrow) in a femoral head with periarticular tumoral calcinosis in a case of long-standing scleroderma. Undecalcified bone section (Goldner’s Masson Trichrome × 200) with black calcium hydroxyapatite deposits evident in inset (blue arrow) (Von Kossa × 200)