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Decreased BW and adipose mass in Ob/Ob rescue mice. (a) Leptin levels in plasma of mice taken at terminal necropsy. (b) Body composition, determined by EchoMRI. Data represented as mean ± SD (n = 4 to 5). Significance determined by one-way ANOVA. *P < 0.05; **P < 0.01; ****P < 0.0001.
