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MEF transplants sustain protection over the long term. (a) At ~7 months of age, plasma leptin levels measured from blood taken from mice at terminal necropsy. (b) Body composition determined by EchoMRI. (c) Liver weight and (d) plasma insulin levels measured from blood taken from mice at terminal necropsy. Data represented as mean ± SD (n = 3 to 4). Significance determined by one-way ANOVA. **P < 0.01; ****P < 0.0001.
