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. 2018 Aug 25;13:60. doi: 10.1186/s13000-018-0742-8

Fig. 3.

Fig. 3

A PD-L1 negative case with a mild lymphocyte density, low HIF-2α expression, and high HIF-1α expression (× 400). a No PD-L1 staining. b PD-1-positive mild lymphocytic infiltration, c CD4-positive mild lymphocytic infiltration. d CD8-positive mild lymphocytic infiltration, e Negative HIF-2α expression. f High-score HIF-1α expression