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IL-22 expression was increased in aGVHD mice. aGVHD was induced as described in Materials and Methods. Mice were sacrificed, and the serum and spleen were collected. IL-22 expression in (a) serum and (b) spleen cells was tested by ELISA. Data are shown as the mean ± SEM from five independent experiments. ∗∗∗ p < 0.001.
