Table 4.
Cox regression analysis of hazard ratios of predictors of discontinuation of breast cancer patients seen at UCH, Ibadan, 2001-2010.
| Variable | HR | 95%CI | P-value |
|---|---|---|---|
| Development of metastasis | |||
| There is metastasis | 1.793 | 1.396-2.302 |
<0.001 |
| No metastasis | 1.00 | ||
|
| |||
| Baseline packed cell volume (PCV) | |||
| Low (anaemia) | 1.404 | 1.120-1.760 |
0.005 |
| Normal (no anaemia) | 1.00 | ||
|
| |||
| Stage at presentation (Manchester stage) | |||
| Early stage (Stage I&II) | 1.310 | 1.047-1.639 |
0.015 |
| Late stage (Stage III&IV) | 1.00 | ||
|
| |||
| Duration of symptoms before diagnosis | |||
| ≤ 12 months | 0.833 | 0.660-1.051 | 0.123 |
| > 12 months | 1.00 | ||
|
| |||
| Menopausal status | |||
| Premenopausal patients | 1.063 | 0.794-1.425 | 0.680 |
| Postmenopausal patients | 1.00 | ||
|
| |||
| Age | |||
| Younger patients | 1.415 | 1.044-1.917 | 0.52 |
| Older patients | 1.00 | ||
|
| |||
| Marital status | |||
| Not Married | 1.256 | 0.964-1.637 |
0.091 |
| Married | 1.00 | ||
CI = confidence interval; HR = hazard ratio; 1.00 = reference category.