Table 6.
The expression difference of Nrf2 and HO-1 mRNA and protein between groups.
Control group (n = 20) | OSAHS group (n = 20) | P value | |
---|---|---|---|
Nrf2 mRNA | 0.30 ± 0.097 | 0.16 ± 0.05 | ≤0.001∗∗a |
HO-1 mRNA | 0.050 (0.042–0.065) | 0.039 (0.029–0.048) | 0.004∗∗b |
Total Nrf2 protein | 0.53 ± 0.088 | 0.32 ± 0.073 | ≤ 0.001∗∗a |
Nrf2 protein at the nucleus | 0.66 ± 0.15 | 0.28 ± 0.07 | ≤0.001∗∗a |
HO-1 protein | 0.62 ± 0.12 | 0.30 ± 0.13 | ≤0.001∗∗a |
Nrf2, nuclear factor erythroid 2-related factor 2; HO-1, heme oxygenase-1. aStudent's t-test (data are presented as mean ± SD). bMann–Whitney U test (data are presented as median (minimum-maximum)). ∗∗p < 0.01.